Azacitidine and lenalidomide combination: a novel relapse prophylaxis regimen after allogeneic hematopoietic stem-cell transplantation in patients with acute myeloid leukemia

IntroductionWhile allogeneic hematopoietic stem cell transplantation (allo-HSCT) can be a curative regimen for acute myeloid leukemia (AML), relapse of AML remains a serious risk post-transplantation.Once relapsed, salvage options are limited and management of AML is difficult.Here we designed a prospective study to examine the efficacy and tolerab

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Intracellular Habitation of Staphylococcus aureus: Molecular Mechanisms and Prospects for Antimicrobial Therapy

Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a global health threat, especially with the continuous development of antibiotic resistance.As an opportunistic Facial Cleansers pathogen, MRSA infections have a high mortality rate worldwide.Although classically described as an extracellular pathogen, many studies have shown over t

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Lessons Learned from Crowdsourcing Complex Engineering Tasks.

Crowdsourcing is the practice of obtaining needed ideas, services, or content by requesting contributions from a large group of people.Amazon Mechanical Turk is a web marketplace for crowdsourcing microtasks, such as answering surveys and image tagging.We explored the limits of crowdsourcing by using Mechanical Turk for a more complicated task: ana

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